The Effect of Anti-Diabetics in Kidney of Rats

The optimization of this study is anti-diabetic effect in kidney of albino wistar rats using Gymnema sylvestre (Retz) R.Br. herbal powder. The histopatholoical and biochemical assays were carried out in organ and blood serum of kidney. The different concentration of powder treated as 5, 10, 15, 20/gms/25 days. The effect of crude drugs in rats reduced the body weight and extent of diabetics was assessed in kidney by measuring the levels of selected blood parameters of protein, glucose, cholesterol, insulin and triglycerides and the effect of histopathology. The crude drugs reduced the body and kidney weight of animals and reduced significant level of insulin, protein, triglycerides, cholesterol and glucose. The data was analyzed using mathematical calculations values were expressed as significant.