Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma

Donna E. Reece,Daniel M. Sullivan,Sagar Lonial,Ann Mohrbacher,Gurkamal S. Chatta,Chaim Shustik,Howard A. Burris,Karthik Venkatakrishnan,Rachel Neuwirth,William Riordan,Michael Karol,Lisa L. von Moltke,Milin Acharya,Peter Zannikos,A. Keith Stewart

Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma

2011

Donna E. Reece
Daniel M. Sullivan
Sagar Lonial
Ann Mohrbacher
Gurkamal S. Chatta
Chaim Shustik
Howard A. Burris
Karthik Venkatakrishnan
Rachel Neuwirth
William Riordan
Michael Karol
Lisa L. von Moltke
Milin Acharya
Peter Zannikos
A. Keith Stewart

Purpose Characterize bortezomib pharmacokinetics/pharmacodynamics in relapsed myeloma patients after single and repeat intravenous administration at two doses.

Keywords:

Prospective cohort study
Pharmacodynamic Study
Pharmacodynamics
Bortezomib
Pharmacology
Proteasome Inhibition
Multiple myeloma
Medicine
Pharmacokinetics
Drug
in patient

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