Caffeic acid oligomers from Mesona chinensis and their In Vitro antiviral activities.

Abstract The phytochemical study of the aerial part of Mesona chinensis led to the isolation of five new caffeic acid oligomers (1–5), as well as four known analogues (6–9). The structures of the new compounds including their absolute configurations were elucidated by comprehensive spectroscopic analysis, chemical method, and quantum-chemical electronic circular dichroism (ECD) calculation. Among the isolates, compound 7 showed significant in vitro antiviral activity on respiratory syncytial virus (RSV).