Advances in long non-coding RNA in prostate cancer

Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nt without any protein coding ability. LncRNAs perform biological functions through a variety of mechanisms. They have a close association with human tumors, regulating the expression of genes at the epigenetic, transcriptional and post-transcriptional levels. LncRNAs are wildly involved in biological and pathological process and play a significant role in the development of cancer. This article reviews the research in the current status of lncRNAs in prostate cancer. DOI:10.3781/j.issn.1000-7431.2014.02.015