Epigallocatechin gallate (EGCG) suppresses epithelial-Mesenchymal transition (EMT) and invasion in anaplastic thyroid carcinoma cells through blocking of TGF-β1/Smad signaling pathways

Tingting Li,Ning Zhao,Jie Lu,Qingli Zhu,Xinfeng Liu,Fengyun Hao,Xuelong Jiao

Epigallocatechin gallate (EGCG) suppresses epithelial-Mesenchymal transition (EMT) and invasion in anaplastic thyroid carcinoma cells through blocking of TGF-β1/Smad signaling pathways

2019

Tingting Li
Ning Zhao
Jie Lu
Qingli Zhu
Xinfeng Liu
Fengyun Hao
Xuelong Jiao

ABSTRACTTransforming growth factor (TGF)-β1 plays a crucial role in the epithelial-to-mesenchymal transition (EMT) in many cancer types and in thyroid cancers. Epigallocatechin-3-gallate (EGCG), th...

Keywords:

Cancer
Epithelial–mesenchymal transition
SMAD
Cancer research
Thyroid
Signal transduction
Transforming growth factor
Epigallocatechin gallate
Growth factor
Chemistry

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