Prevention of poststroke depression with milnacipran in patients with acute ischemic stroke: A double-blind randomized placebo-controlled trial

Poststroke depression (PSD) is one of the most frequent neuropsychiatric consequences of stroke. It has been shown to be associated with both impaired recovery and increased mortality. The purpose of this study is to investigate the prophylactic effect of milnacipran in PSD. Ninety-two patients were