The Rola mikrobiomu jelitowego w funkcjonowaniu układu nerwowego

The microbiome that inhabits the human body significantly affects its development, functioning, homeostasis and intestinal barrier tightness. It turns out that it also has a significant impact on the functioning and development of the nervous system. Individual pathways of communication between the gut microbiota and the central nervous system, which include bacterial metabolites, the vagus nerve, the immune system and the hypothalamicpituitary-adrenal axis, form the so-called cerebral-intestinal axis. It plays an important role in the pathogenesis of many diseases, such as inflammatory bowel diseases, fatty liver disease, psychiatric disorders and food allergies. It also plays an important role in the process of growing up and aging. A thorough understanding of the mechanismsthat work on its path will help to reduce the risk of these diseases and their more effective treatment, by appropriate modification of the intestinal microbiome.