Dose finding study of varlitinib ± trastuzumab with carboplatin/paclitaxel in advanced solid tumors.

Matilda Lee,Andrea Li Ann Wong,Samuel Guan Wei Ow,Raghav Sundar,Lingzhi Wang,David Shao Peng Tan,Ross A. Soo,Cheng Ean Chee,Valerie Heong,Ying-Chen Chen,Joline Si Jing Lim,Wei Peng Yong,Siew Eng Lim,Boon C. Goh,Soo-Chin Lee

Dose finding study of varlitinib ± trastuzumab with carboplatin/paclitaxel in advanced solid tumors.

2018

Matilda Lee
Andrea Li Ann Wong
Samuel Guan Wei Ow
Raghav Sundar
Lingzhi Wang
David Shao Peng Tan
Ross A. Soo
Cheng Ean Chee
Valerie Heong
Ying-Chen Chen
Joline Si Jing Lim
Wei Peng Yong
Siew Eng Lim
Boon C. Goh
Soo-Chin Lee

2588Background: Varlitinib (V) is a reversible inhibitor of HER1/HER2/HER4. This is a phase 1b dose confirmation study to determine safety and early efficacy signals of V ± T combined with weekly P...

Keywords:

Carboplatin/paclitaxel
Oncology
Trastuzumab
Pathology
VARLITINIB
Internal medicine
Medicine
dose finding

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