RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition
2017
Background
RAC3 coactivator overexpression has been implicated in tumorigenesis, contributing to inhibition of apoptosis and autophagy. Both mechanisms are involved in resistance to treatment with chemotherapeutic agents. The aim of this study was to investigate its role in chemoresistance of colorectal cancer.
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