Metodological and diagnostic relevance of IgEs to recombinant allergens Api m 1 and Ves v 5 determined by the multiplex test ImmunoCAP ISAC.

ImmunoCAP ISAC (ISAC, Phadia, Uppsala, Sweden) helps to reveal the IgE sensitization profile of multisensitized patients and the potential risk for severe reactions.1 It is also useful for identifying cross-reactive IgE patterns and might direct the treatment of allergic disease.1 This multiplex allergen test enables the measurement of IgE antibodies to a fixed panel of 112 components from 51 allergen sources in a single step, including two major venom components, honeybee rApi m1 and yellow jacket rVes v5 and two additional marker allergens, Api m4 and Pol d5.