[Clinical analysis of upper airway resistance syndrome and obstructive sleep apnea-hypopnea syndrome in children].

Objective To analyze the similarities and differences of the clinical manifestations between the children with upper airway resistance syndrome （UARS） and obstructive sleep apnea-hypopnea syndrome （OSAHS）, and to explore the clinical features and characteristics of sleep respiratory parameters. Methods Using the double-blind method, all children were diagnosed as UARS or OSAHS through the polysomnography test and the results of all children were analyzed by a sleep technician and an otolaryngologist. Another ENT doctor recorded their clinical and physical examination in detail. Results Polysomnography showed that the apnea-hypopnea index（AHI） and the lowest oxygen in 253 children with OSAHS were 3.60 [ 2. 00 ;7.55 ] times/h and 0. 90 [ 0. 85 ;0. 91 ], and were 0.90 [ 0. 50 ; 1.10 ] times/h and 0. 95 [ 0. 92;0.96 ] in 102 children with UARS, the difference of the two groups by rank test was statistically significant. The proportion of UARS and OSAHS was more common during preschool period than during school-age period. The chief complaint in two groups was sleep snoring, and the main symptoms were sleep restless, attention deficit/hyperactivity and breath with mouth open. The incidence rate of above symptoms were as follows, 94. 1% ,72. 5% ,62. 7% and 37.3% in children with UARS, 92. 9% ,78.7% ,57. 7% and 45.5% in children with OSAHS. The difference was not significant by chi-square test （ P > 0.05 ）. Tonsil and adenoid hypertrophy were also observed in the two groups, the difference was not significant （ X^2 = 0. 27, P = 0. 87）. However, the children with OSAHS were more apt to have the sleep apnea than with UARS, the difference was statistically significant （ X^2 = 34. 07, P < 0. 001 ）. Conclusions The clinical manifestations of two groups are similar, the difference between UARS and OSAHS can not be determined by the patient's clinical performance. Sleep apnea can be more easily observed in children with OSAHS than that in UARS,; the final diagnosis is based on polysomnography. Key words: Sleep apnea, obstructive; Sleep apnea syndromes; Child; Airway resistance