Bioelectrical impedance analysis-derived phase angle is related to risk scores of a first cardiovascular event in adults

Abstract Objective The aim of this study was to investigate the association between phase angle (PhA) and first cardiovascular (CV) event risk. Methods This is a cross-sectional study. PhA was determined using a single-frequency bioelectrical impedance analyzer. The American College of Cardiology/American Heart Association (ACC/AHA) (n=455; men=49%) and the Framingham General Cardiovascular (FRS-CVD) (n=489; men=49%) scores were used to estimate the risk of a first CV event in adults. Logistic and multinomial regressions were used to evaluate the relationship between ACC/AHA and FRS-CVD risk scores (outcomes) and PhA. Additionally, the consumption of in natura or minimally processed foods was included in the models as an adjustment variable. Results Men and women, classified according to ACC/AHA (P 7.3°) was associated with a CV lower-risk (ACC/AHA, OR 0.28, 95%CI 0.14-0.56; FRS-CVD, RRR 0.11, 95%CI 0.03-0.37). The adjustment of all models for consumption of in natura or minimally processed foods did not change the results. Conclusion Higher PhA values were associated with lower-risk of a first CV event in men classified in higher-risk categories. In natura or minimally processed foods consumption did not influence the relationship between PhA and CV-risk. These results may encourage future research about possible applications of PhA as an additional index in CV primary prevention.