Demography, expectations and experiences of oocyte donors in northern India − an interview-based study

Study question: Oocyte donation is an increasingly popular treatment option for pregnancy and parenthood in women with poor ovarian reserve or advanced age. Indian literature still lacks a formal study focusing on expectations and experiences of oocyte donors. Aim: To assess demography, expectations and experiences of oocyte donors in northern India by an interview-based questionnaire. Material and Methods: This is a prospective cross-sectional study at a tertiary care IVF centre from August 2018 to January 2019. Sample size was 65 oocyte donors found fit and willing for egg donation. Interviews were taken using structured questionnaire at the time of registration and after successful oocyte retrieval. Results: Mean age of donors was 25 years. Most of the donors were housewives (70%) and rest were in a private job. Only 29% of donors were educated above tenth standard. Almost all the donors (96%) were commercial donors introduced by paid agents or friends. Most of the donors had very poor understanding of details of the oocyte retrieval procedure. Only 36% of donors felt that compensation given is adequate, rest expected a higher compensation. Average compensation given to donors was INR 15,000–25,000, which was 5000–10,000 less than their expectations. All donors were satisfied with the procedure and did not feel exploited or anxious or depressed but few complained of discomfort experienced in visits and minimal complications like pain, nausea, and fever. None of the donors developed signs/symptoms of OHSS. Average number of oocytes retrieved per donor was 17. Mean dose of gonadotropins required per donor was 1495 IU. Conclusion: Our findings show that the oocyte donation has an overall good acceptance and satisfaction among the donors. However there is a need to impart more detailed information to donors in order to prevent their possible exploitation.