[Changes in cerebral hemodynamics in chronic users of "PACO" and cocaine: case-control study].

OBJECTIVE: To assess if there are changes in brain hemodynamics evaluated by means of transcranial doppler's flow velocity, pulsatile index and cerebral perfusion pressure, between cocaine chronic abusers and healthy volunteers. METHOD: Prospective, case and control, observational study. Sex, age, user history, vital signs and transcranial doppler findings.Statistical analysis was performed by means of normality test, Wilcoxon's test for non parametric samples and T Student test. RESULTS: Fifty-three abusers and 35 healthy volunteers were studied. Statistical differences were found for a diminish in age(p=0.008) and cerebral perfusion pressure in all cerebral arteries (p

Keywords:

• Hemodynamics
• Case-control study
• Anesthesia
• Medicine
• Cerebral perfusion pressure
• Resuscitation
• Vital signs
• Cerebral arteries
• Pulsatile flow
• Transcranial Doppler

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