Quinazoline addition to indole hydrazone derivatives in TFA as a facile synthesis of trifluoroacetylhydrazide quinazoline σ-adducts

Addition of indole 3-carbaldehyde arylhydrazones to quinazoline in trifluoroacetic acid occurs at the C5-atom of the indole moiety affording quinazoline σ-adducts with indole and trifluoroacetylhydrazide moieties.