Report of the Fourth International Workshop on Human Chromosome 22 Mapping 1994

The third international workshop on the mapping of human chromosome 22 was held at the Sugarloaf Conference Center in Philadelphia Pennsylvania USA from September 17--20, 1992. It was organized by Beverly S. Emanuel of Children`s Hospital of Philadelphia and the Human Genome Center for Chromosome 22. The highlights of the conference included the discussion of the chromosome 22 gene at the Ewings Sarcoma breakpoint, the identification of a polymorphic TG/CA repeat containing locus tightly linked to the NF2 gene, the isolation of a candidate tumor suppressor locus for meningioma, the isolation of numerous as yet uncharacterized new cDNAs for chromosome 22 and the progress which has been made on generating physical and genetic maps of the chromosome. There is a new genetic map comprised of 16 short tandem repeat polymorphism (STRP) markers of which 12 have greater than 70% heterozygosity (Fig. 1). It was decided that the next meeting should be held in 18 months and it will be organized by Peter Scambler in the United Kingdom.