Relevant Discordance Between 68Ga-DOTATATE and 68Ga-DOTANOC in SDHB-Related Metastatic Paraganglioma: Is Affinity to Somatostatin Receptor 2 the Key?

AbstractPheochromocytomas/paragangliomas are somatostatin receptor 2–overexpressing tumors. 68Ga-DOTA-peptide imaging has recently shown excellent results in the detection of metastatic lesions in these tumors. However, currently used 68Ga-DOTA peptides show different somatostatin receptor affinitie