Impact of persistent endotracheal tube biofilm on ventilator-associated pneumonia clinical and microbiological response

Ventilator-associated pneumonia (VAP) is the most common infectious complication in critically ill patients. The formation of biofilm on endotracheal tube (ETT) surface plays an important role in pathogenesis of this infection, because it facilitates the growth and survival of microorganisms and difficults the action of antimicrobial therapy.