Abstract 13492: Increasing Endothelial Insulin Sensitivity Rescues Vascular Function and Repair in Systemic Insulin Resistance by Restoring Nitric Oxide Bioavailability and Improving Endothelial Cell Migration

Anshuman Sengupta,Nadira Yuldasheva,Hema Viswambharan,Stacey Galloway,Romana S Mughal,Ben Mercer,Noman Ali,Andrew M. Walker,Amir Aziz,Jessica Smith,Anna Skromna,Natallia Makava,Mark T. Kearney,Richard M. Cubbon

Abstract 13492: Increasing Endothelial Insulin Sensitivity Rescues Vascular Function and Repair in Systemic Insulin Resistance by Restoring Nitric Oxide Bioavailability and Improving Endothelial Cell Migration

2015

Anshuman Sengupta
Nadira Yuldasheva
Hema Viswambharan
Stacey Galloway
Romana S Mughal
Ben Mercer
Noman Ali
Andrew M. Walker
Amir Aziz
Jessica Smith
Anna Skromna
Natallia Makava
Mark T. Kearney
Richard M. Cubbon

Introduction: Insulin resistance is independently associated with vascular disease. Insulin receptor haploinsufficient (IRKO) mice are hypertensive and exhibit endothelial dysfunction and impaired ...

Keywords:

Medicine
Endothelial stem cell
Bioavailability
Endocrinology
Endothelial dysfunction
Insulin resistance
Vascular disease
Insulin receptor
Haploinsufficiency
Nitric oxide
Internal medicine

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