Living kidney donor evaluation for all candidates with normal estimated GFR for age.

Background Multiple-days-assessments is frequent for the evaluation of candidates to living kidney donation, combined with an early GFR estimation (eGFR). Living kidney donation is questionable when eGFR is Methods We compared the evolution of eGFR after donation between three groups of pre-donation eGFR: normal for age (Sage ) higher than 90 or 80 mL/min/1.73m2 (S90 and S80 respectively); across three age groups ( 55 years) in a population of 1825 French living kidney donors with a median follow-up of 5.9 years. Results In donors younger than 45, post-donation eGFR, absolute- and relative-eGFR variation were not different between the three groups. For older donors post-donation eGFR was higher in S90 than in S80 or Sage but other comparators were identical. Post-donation eGFR slope was comparable between all groups. Conclusions Our results are in favor of in-depth screening for all candidates to donation with a normal eGFR for age.