Application of Fluorescent in Situ Hybridization (FISH) in Surgical and Cytologic Specimens (Solid Tumors, Hematopoietic Tumors, Urine, Bile Duct Brushing and Bronchoscopy)

Florescence in situ hybridization (FISH) using chromosome-specific probes has become an important cytogenetic tool in the evaluation of many congenital disorders, hematologic malignancies, some solid tumors and cytologic neoplasm. Due to its interphase analysis, fast, high sensitivity and specificity, both fresh and fixed specimens, it becomes a very informative and rapid adjunct to standard karyotyping.