o-054 materno-fetal cardiovascular complications after oocyte donation in turner syndrome: a very high-risk pregnancy

centile) in 31%. We report also a bronchopulmonary dysplasis after severe hyaline membrane disease and an acute stroke. conclusions: Pregnancies in TS after OD are at very high risk since only 33% were in our cohort associated with an absolutely normal maternofetal outcome. The most frequent maternal risk was represented by PAHD (38.5%) unrelated in our cohort with age, BMI or hGH treatment but likely linked to Turner arteropathy, small uterus and OD itself. PAHD is associated with fetal hypotrophy which represents the most frequent neonatal complication. The stress of pregnancy, especially in case of PAHD, increases the risk of aortic rupture that is already high in young women with TS as illustrated by the 2 fatal cases out of our 76 pregnancies. Our data clearly illustrate the need for tight recommendations including: 1) a systematic pregravidic cardiovascular evaluation with at least echocardiogram and/or thoracic RMN with aortic measurement normalized to body surface area; 2) complete information to patients; 3) elective single