Synthesis of the 7-Azaindole (1H-Pyrrolo[2,3-b]pyridine) Analogous to Cannabimimetic JHW 200.

Abstract Cannabinoid agonists have been suggested to have potential therapeutic uses. The synthesis of a new cannabimimetic analogue of JHW 200 possessing a 7‐azaindole unit instead of an indole moiety is described. The approach used for indole derivatives failed, and a new strategy that involves the reaction of a nitrile and 1‐naphtyl magnesium bromide was studied.