Long-term use of Pegfilgrastim in children with severe congenital neutropenia: clinical and pharmacokinetic data

To the editor: Severe congenital neutropenia (SCN) is a rare disease characterized by a severe defect in neutrophil production and by high risks of lethal infection.[1][1],[2][2] Lifetime treatment with granulocyte colony-stimulating factor (G-CSF) is indicated in patients responding to standard