Characteristics of pharmaceutical drugs' profile used by diabetic 2 patients from Bauru's diabetics association (BDA), regarding to class, frequency of use, associations and interactions

Introduction: Diabetes mellitus (DM) is a chronic disease caused by genetic, metabolic and/or acquired factors that cause insulin deficiency or resistance that result in hyperglycemia. Objective: to characterizing pharmaceutical drugs profile in that concerns the frequency of use, pharmacological classes and possible associations and interactions Method: This prospective study was done by applying a questionnaire to 62 individuals with diabetes mellitus 2 (DM2) that have been watched by educational activities at Bauru's Diabetics Association (BDA. ATC classification (Anatomical Therapeutic Classification/2008) was used for pharmaceutic drug classification. Results:The group A (alimentary tract and metabolism) showed to be the most used (54%), followed by group C (cardiovascular) (33%). Metformin (52%) and glyburide (25%) were the most used oral hypoglycemic agents (OHA), with only 10% being in use of insulin, alone or associated with other drugs. Metformin was the most used in multiple therapies. Discussion: Although the assessment of pharmacotherapeutic follow-up of patients were observed 23 potential drug interactions between combinations of drugs used.The need of different therapies for DM2 is justified by the occurrence of other com orbidities such as hypertension, obesity and dyslipidemia. However, in many cases, the use of all these drugs together can lead to drugs interactions deteriorating patient's quality of life. Conclusion: the multidisciplinary team approach is to be aware of the prescribed drugs to DM2 and teach them the correct use these drugs in such a way that patient's quality of life not be endangered or worsened. Introducao: Diabetes mellitus (DM) e uma doenca cronica causada por fatores geneticos, metabolicos e / ou adquiridas que causam deficiencia de insulina ou resistencia que resultam em hiperglicemia. Objetivo: caracterizar o perfil de drogas farmaceuticas, no que diz respeito a frequencia de uso, classes farmacologicas e possiveis associacoes e interacoes. Metodologia: este estudo prospectivo foi realizado com a aplicacao de um questionario a 62 individuos com diabetes 2 (DM2) que compareceram as atividades educativas da Associacao de Diabeticos de Bauru (ADB). A Classificacao ATC (Anatomical Therapeutic chemical/ 2008) foi utilizada para a classificacao das drogas farmaceuticas. Resultados: drogas do grupo A (trato digestivo e metabolismo) mostrou ser a mais utilizada (54%), seguidos pelos do grupo C (cardiovascular) (33%). Metformina (52%) e glibenclamida (25%) foram os hipoglicemiantes orais mais utilizados, com apenas 10% em uso de insulina, isoladamente ou associados a outras drogas. A metformina foi a mais utilizada em terapias multiplas. Discussao: na avaliacao do seguimento farmacoterapeutico dos pacientes foram observadas 23 interacoes medicamentosas potenciais entre as combinacoes de medicamentos utilizados. A necessidade de diferentes terapias de DM2 e justificada pela ocorrencia de outras co-morbidades como hipertensao, obesidade e dislipidemia. No entanto, em muitos casos, a utilizacao de todas estas drogas em conjunto, podem levar a interacoes de drogas que deterioram a qualidade de vida do paciente. Conclusao: a abordagem da equipe multidisciplinar consiste em estar consciente dos medicamentos prescritos para DM2 e ensinar o uso correto deles de tal forma que a qualidade de vida do paciente nao tenha riscos ou piora.