Hypertension and aortic dissection in patients with hypertension and pre-hospital characteristics antihypertensive therapy

Objective: To summarize hypertension characteristics and pre hospital antihypertensive therapy in patients with hypertension and aortic dissection, to explore the measures of prevention and control. Methods: 683 patients with hypertension complicated with aortic dissection patients (AD group), 8974 patients with hypertension (hypertension group), during the five years from October 2009 to October 2014, were analyzed retrospectively according to the hospital medical records data combined with outpatient clinical data.Retrospective analysis of hypertension characteristics and pre hospital antihypertensive therapy from the two groups of patients when first diagnosed was conducted. Results: The two groups ratio of diabetes, coronary heart disease, hyperlipidemia, renal insufficiency, have no statistical difference. Most patients in AD group have over 10 years’ history of hypertension ( P <0.05).The incidence of aortic dissection in men of AD group is higher than the hypertensive group（ P <0.05）. The ratio of 40～60 years in AD group is more than that in hypertensive group ( P <0.05). The ratio of stage 3 hypertension in AD group is more than that in hypertension group ( P < 0.05).The ratio of no antihypertensive treatment in patients in the AD group is more than that in hypertension group ( P < 0.05).The average age of onset in AD group was lower than that in hypertension group ( P <0.05). The ratio of patients in the AD group treated with ARB or ACEI antihypertensive was lower than that in hypertension group ( P <0.05). Conclusion: Hypertension complicated with aortic dissection is mostly accompanied by more than 10 years’ history of hypertension in most male patients of 40～60 age group, with grade 3 hypertension. Most did not receive antihypertensive treatment, the average age of onset is low, using ARB or ACEI for the treatment of patients is less.