Cytotoxic and thrombolytic activity of roots of Musa paradisiaca (Linn)

The study was aimed to evaluate the cytotoxic and thrombolytic activity of methanol extract of Musa paradisiaca. The cytotoxic activity of the crude extract was determined by using brine shrimp lethality bioassay and LC50 values of the sample were 22.336 ± 0.41μg/ml whereas for standard vincristine sulfate was 8.50 ± 0.16μg/ml as a positive control. In thrombolytic activity using in vitro clot lysis method, the plant’s extract showed (46.26 ±1.54%) clot lysis as compared to standard streptokinase (67.32±0.34%).