Синтез биологически активных антиоксидантов в реакции этерификации 2-(n-ацетиламид)-3-(3’,5’-ди- трет. Бутил-4’-гидроксифенил)пропионовой кислоты

In the reaction esterification 2(N-acetylamid)-3(3 ’, 5 '-di-tert.butyl-4 '-hydroxyphenyl) propionic acid by alcohols (MeOH, Et ОН, isoPrOH, n-BuOH, n-C 9H 17OH) in the presence of SOCl 2 5 antioxidants with yields of 90-94 % are synthesised. Antioxidative properties of compounds on value к 7 at level 2.10 6 l.mol -1.s -1 that above, than for methyl ester (3 ’, 5 '-di-tert.butyl-4 '-hydroxyphenyll) propionic acid ( к 7 =2.10 4 l.mol -1.s -1). Are executed quantovo-chemical calculations of structure of methyl ester 2-(N-acetylamid)-3-(3 ’, 5 '-di-tert.butyl-4 '-hydroxyphenyl) propionic aci d which explain communication of entropy and structure with antioxidative properties.