Longitudinal evaluation of bone mass in adolescents and young adults with juvenile idiopathic arthritis: the role of bone mass determinants in a large cohort of patients

significantly increased levels of fat CSA than controls (p < 0.0001). Finally, JIA patients presented a significantly reduced AD-SoS (p < 0.001), and QUS z-score (p < 0.005). These data were confirmed also in longitudinal evaluation. However, evaluating different treatments, we showed a significant negative correlation among aBMD value (p < 0.005), TrabBMD (p < 0.005), AD-SoS (p < 0.005), and systemic corticosteroids exposure or intraarticular corticosteroids injections, and a positive correlation among TNF-alpha-blocking agents and aBMD (p < 0.005), TrabBMD (p < 0.005), and AD-SoS (p < 0.005).