Assembly and Analysis of Next-Generation Sequencing Data

RNA sequencing (RNA-seq) has become a major method for the analysis of the transcriptome. In the course of this PhD project, more than 1,500 RNA-seq samples have been analyzed. An automated RNA-seq data analysis pipeline was implemented to allow for a convenient and user-friendly way to process these data. On top of that, different methods and parameters were investigated in order to provide reliable results. These results are stored in a relational database and can be browsed via a web application.