The intravascular contrast agent Clariscan™ (NC 100150 injection) for 3D MR coronary angiography in patients with coronary artery disease

In our experience ClariscanTM improves image quality, thus, increasing the visual length and improving the actual visible dimensions of the coronary arteries. Distal segments improved to a higher extent than the proximal parts. In that way sensitivity and specificity for the detection of significant coronary artery disease could be improved. Better SNR and CNR can be used to improve spatial resolution or to reduce scan time by techniques like SENSE or SMASH [14,15].