Undertreatment of Cardiovascular Risk factors in the Type 1 Diabetes Exchange Clinic Network (USA) and the Prospective Diabetes Follow-up (Germany/Austria) Registries.

AIM: To examine the control of cardiovascular risk factors in type 1 diabetes (T1D) registries from the USA and Germany/Austria. MATERIALS AND METHODS: Data on individuals aged >/=12 years with T1D for >/=1 year, from the T1D Exchange Clinic Network (T1DX, USA) and the Prospective Diabetes Follow-up Registry (DPV, Germany/Austria) between 1/1/2016 and March 31, 2018 were analyzed. Linear and logistic regression models adjusted for age groups, sex, duration of diabetes, and minority status were used to compare clinical characteristics and achievement of diabetes management targets between registries. RESULTS: The cohort included 47 936 patients (T1DX n = 19 442; DPV n = 28 494). Achievement of A1c goals ( /= 65 years) in the T1DX achieved A1c goal of <7.5% compared to DPV (70% vs 50%, p < 0.001). Frequency of patients with overweight (53% vs 51%, p < 0.001) and obesity (19% vs 9%, p < 0.001) was higher in T1DX. Frequency of meeting blood pressure goals (84% vs 66%, p < 0.001) and lipid goals (73 vs 62%, p < 0.001) was higher in T1DX; this was observed across all age groups (all p < 0.001). Few young adults <26 years received antihypertensive and lipid lowering medications, respectively, despite indications in both registries (T1DX: 5% and 3%, DPV: 3% and 1%). CONCLUSION: A minority of patients with T1D achieve glycemic targets and the majority are inadequately treated for hypertension and dyslipidemia. This highlights the need for improved diabetes and cardiovascular risk management strategies in T1D. This article is protected by copyright. All rights reserved.