Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor: activities on endothelial cells
1993
Granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor were considered as growth and differentiation factors restricted to hematopoietic cells. It was recently found that non-hematopoietic cells, including endothelial cells, respond to these cytokines. In this review we describe their effects on endothelial cells, underlining their role in the behavior and survival of the microenvironment of bone marrow, in the angiogenesis process related to the progression of solid tumors and of vascular tumors, and in the homing of lymphocytes.
Keywords:
- Vascular endothelial growth factor C
- Myeloid-derived Suppressor Cell
- Vascular endothelial growth factor A
- Granulocyte macrophage colony-stimulating factor receptor
- Granulocyte colony-stimulating factor receptor
- Angiogenesis
- Immunology
- Macrophage colony-stimulating factor
- Cell biology
- Granulocyte macrophage colony-stimulating factor
- Biology
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