2‐(Pyridin‐2′‐yldisulfanyl)ethoxycarbonyl Chloride

[892402-96-9] C8H8ClNO2S2 (MW 249.74) InChI = 1S/C8H8ClNO2S2/c9-8(11)12-5-6-13-14-7-3-1-2-4-10-7/h1-4H,5-6H2 InChIKey = LDKUPCIUFTUUCQ-UHFFFAOYSA-N (heterobifunctional cross-linking reagent, self-immolative linker)1-3 Alternate Name: carbonochloridic acid, 2-(2-pyridinyldithio)ethyl ester. Solubility: soluble in DMF, DMSO, dichloromethane, MeCN, and THF. Preparative Method: the reagent has been prepared by reaction of 2-(pyridin-2′-yldisulfanyl)ethanol with diphosgene or triphosgene.1, 2, 4 The crude reaction mixture is commonly concentrated under reduced pressure and then reconstituted and used immediately without purification.