Myocardial asynergy of the left ventricle in patients with aortic stenosis

: Left ventriculograms obtained from 21 patients without any intracardiac hemodynamic abnormalities were analyzed by using the correlation method. The analysis revealed three functional areas of the left ventricle and defined normal values of their systolic and diastolic pulses. Hypo- and hyperkinesia of the functional areas in the left ventricle were quantitatively determined. Left ventricular cinematics was studied in 105 patients with aortic stenosis. Most patients of them were demonstrated regional cinematic abnormalities of various genesis. Local or total hypokinesia was detected in 62 per cent; hyperkinesia of its upper areas was found in a third; 7 per cent had normal dynamics of contraction in all the functional areas. It should be taken into account heterogeneous responses of the left ventricle to systolic overload while performing all investigations and studies or making clinical and prognostic assessments.