Cine MRI evaluation of fasting and postprandial gastric motility

Objective To evaluate the feasibility of cine MRI for assessment of fasting and postprandial gastric peristaltic activity as well as antral motility.Methods Eleven healthy volunteers fasted for 6 h prior to the examination underwent cine MRI in a right decubitus position with steady-state acquisition(2D FIESTA) sequences.The proximal and distal parts of stomach were examined before and 5,15,30 minutes after ingestion.Gastric peristaltic activity and motility were quantified by calculating the percentage occlusion of gastric contractions(PGC) and the gastric motility index(GMI).Results The gastric peristaltic wave was observed clearly on cine MRI.Before ingestion,peristaltic waves appeared in proximal parts of stomach in 4 volunteers and distal parts of stomach in 7 volunteers,while after ingestion it was observed in all volunteers.After ingestion,PGC in proximal and distal parts of stomach were larger than that under fasting state(both P=0.003).The gastric motility index could not be acquired in 2 volunteers.For the other 9 volunteers,the gastric motility index at 15 min after ingestion was higher than that at 5 min(F=6.152,P=0.005),but decreased at 30 min compared with 5 min and 15min(5 min: F=1.624,P=0.238;15 min: F=0.844,P=0.198).Conclusion Cine MRI is a reliable and noninvasive technique for quantitative measurement of gastric peristaltic activity and gastric motility.