Nano structured spinel Co3O4-catalyzed four component reaction: A novel synthesis of Ugi adducts from aryl alcohols as a key reagent

Abstract A simple one pot procedure for the synthesis of α -amino acyl amide with chromone, indole, and napthalene substitution pattern is presented. This protocol involves the nano structured spinel Co 3 O 4 catalysed coupling of aryl alcohols, anilines, carboxylic acids and tert -butyl isocyanide. The salient features of this protocol were simple procedure, mild reaction condition and high yield.