Clinical Characteristics and Outcome of Patients of 2019 Novel Coronavirus Pneumonia with Different Body Mass Index/ 不同体重指数新型冠状病毒肺炎患者的临床特点及转归

Objective To investigate the clinical characteristics and outcome of patients of 2019 novel coronavirus pneumonia with different body mass index, and to evaluate the condition and prognosis Methods The clinical data of 541 patients with COVID-19 diagnosed in Xiaogan Hospital Affiliated to Wuhan University of science and technology from January 16, 2020 to March 28, 2020 were collected The patients were divided into normal weight group, overweight group and obesity group according to BMI Then compared the clinical characteristics and outcomes of the three groups The correlation between BMI and clinical classification was analyzed by ordinal logistic regression Results There were 288 cases (53 23%) in normal weight group, 193 cases (35 67%) in overweight group and 60 cases (11 09%) in obesity group Compared with normal weight group, overweight and obesity group had a higher proportion of hypertension, white blood cells, neutrophils, CRP, ALT, AST, LDH and TG in laboratory test results, and the proportion of severe and critical illness were also higher (P<0 05) After adjusting for age, gender and underlying diseases, regression analysis showed that higher body mass index predict more severe the clinical classification (OR=1 079, 95%CI1 010-1 154) Conclusion In COVID-19 patients, overweight and obese patients are more likely to develop into severe and critical illness, and BMI may be an important risk factor affecting the clinical outcome of COVID-19