Soluble immunoreactivity Treponema pallidum (Treponemapallidum) TpN47 antigen

The present invention includes all antigens on condition that lacks a domain C (amino acids 224-351) of TpN47, at least domain B of the complete TpN47 protein molecule or at least domains A and B,, when including the domain D by, Treponema pallidum ( Treponema pallidum) related to the soluble variant of the antigen 47 (TpN47 antigen). Tpn47 antigen may be fused to a chaperone. Furthermore, the present invention, DNA encoding an the antigen, methods for producing these antigens, as well as for the detection of antibodies to Treponema pallidum in isolated samples, in immunodiagnostic assays, the use of these antigens.