Применение аскорбата лития у лиц среднего возраста с когнитивной дисфункцией

A study evaluating the use of lithium ascorbate in the treatment of cognitive dysfunction involved 200 patients with cerebrovascular disease (mean age 52 years, 92 men, 108 women). Participants were divided into two groups: main (n = 100) — conventional therapy (vascular, nootropic) + lithium ascorbate (at a dose of 780 mg/day) and control (n = 100) — conventional therapy only. The treatment continued for 2 months. In all patients, the level of Li in the hair, the amount of brain-derived neurotrophic factor (BDNF) in the blood plasma, and the neuropsychological status were assessed before and after treatment. It was found that the use of lithium ascorbate in combination with conventional therapy contributed to a significant increase in working efficiency, BDNF level, to mood improvement, as well as an increase in the quality of life of patients in the main group.