Influence of Traditional Chinese Medicine Tiannianyin on Immune Function of Aging Rats

Objective To investigate the influence of traditional Chinese medicine Tiannianyin on immune function of aging rats.Methods 40 SD rats were divided into 4 groups at random: normal group,aging model group,Tiannianyin group and negative control group,each group had 10 rats.The subacutely aging model rats were made by injecting D-gal into abdominal cavity continually.ELISA was used to detect the IL-2 and IL-6 contents in serum,MMT to detect the proliferation and transformation of spleen lymphocyte,and the macrophagic phagocytosis was also observed.Results Tiannianyin not only significantly increased the IL-2 content,the proliferation and transformation of spleen lymphocyte and the macrophagic phagocytosis of aging rats(Tiannianyin group compared with aging group: P0.01,P0.05);but also obviously decreased the IL-6 content of aging rats(Tiannianyin group compared with aging group: P0.01).Conclusion Tianninyin can strengthen the immune function of aging rats,so it has fairly anti-aging effects.