Analysis of Misdiagnosis on 4 Cases of Primary Sclerosing Cholangitis

Objective To analyze the causes of misdiagnosis of primary biliary cirrhosis(PBC).Methods A retrospective analysis was performed on clinical data of 4 patients diagnosed as having PBC during July 2003 and December 2010.Results The ALP,γ-GT,ALT,AST and TBIL of all the patients were higher than normal value at different degrees.4 patients were misdiagnosed.The time needed for correct diagnosis was 12-84 months.The misdiagnosis of the disease was categorized as cholestatic hepatitis,hepatolenticular degeneration and cholelithiasis.Conclusion In order to make a definite diagnosis and avoid or reduce the misdiagnosis rate,the suspected patients with PBC should undertake liverish autoantibody test,and ERCP/MRCP detection.