Accessory pathway ablation in Ebstein anomaly: A challenging substrate.
2021
Background Catheter ablation of accessory pathways (APs) in Ebstein anomaly (EA) has been associated with a high recurrence risk. Objective The purpose of this study was to compare outcomes of AP ablation in EA in an early (1990–2004) vs a recent (2005–2019) era and identify variables associated with recurrence. Methods A retrospective review of all catheter ablations for supraventricular tachycardia in EA at our institution was performed. Results We identified 76 patients with median (25th–75th quartiles) age 9 (2.6–13.3) years. Of these patients, 52 had AP alone, 12 had atrial flutter, 3 had atrioventricular nodal reentrant tachycardia, and 9 had AP plus at least 1 additional arrhythmia. Of the 61 patients with APs, a total of 78 separate APs were identified: 40 right-sided, 37 septal, and 1 left-sided. Acute success for AP first procedure was 89% and did not differ between early and recent eras (89% vs 88%; P = .48). However, 19 patients (31%) required repeat procedures (average 1.4 per patient) due to AP recurrence or ablation failure at first attempt. In comparison to early era, recent era ablations had significantly lower recurrence rates at 1 year (62% vs 19%; P = .005). At median follow-up of 2.5 (0.2–7) years, ultimate AP elimination after all procedures was 93%. Younger age at time of electrophysiological study ( Conclusion Outcomes for AP ablation in patients with EA have improved, but there is still a relatedly high recurrence risk requiring repeat procedures.
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