An convenient method for the synthesis of 7,8-dimethoxy-3-hydroxyquinolin-2(1H-one and its tautomer conformation study
2006
3-Hydroxyquinolin-2(1H)-one (1) was synthesized successfully from readily available 2-nitroveratraldehyde in a three-step reaction. The procedure was based on existing protocol but with slight modification to give a much higher production yield. The tautomer conformation of the quinolinone was studied.
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KQI