Paediatric rheumatology: Corticosteroids as primary therapy in Kawasaki disease

Coronary artery aneurysms affect a substantial proportion of patients with Kawasaki disease, especially when standard therapy fails. Adjunctive primary corticosteroid treatment reduces inflammation and might reduce the incidence of coronary artery disease in a subset of patients at high risk of this comorbidity, but reliably identifying such individuals is a challenge.