Polymerized carbon nanotube paste electrode as a sensing material for the detection of adrenaline with folic acid

A new intuition to construct the sensitive platform based on the poly(phenylmethanoic acid) modified carbon nanotube paste electrode (PPMAMCNTPE) to investigate the electroanalytical performance of adrenaline (AN), which acts as both neurotransmitter and hormone. The PPMAMCNTPE reveals a high detectability than the bare carbon nanotube paste electrode (BCNTPE) through cyclic voltammetry technique. The surface morphology and electrochemical conductivity of the BCNTPE and PPMAMCNTPE was characterized by field emission-scanning electron microscopy and electrochemical impedance spectroscopy. The number of factors affecting the analytical signal were optimized. The lowest detection limit (4.5 × 10–8 M) was gained within a linearity of the AN concentration range of 10–110 µM via differential pulse voltammetry approach at the PPMAMCNTPE. The designed sensor holds a great reproducibility, repeatability, and an outstanding anti-fouling feature. The PPMAMCNTPE possesses an admirable selectivity in the presence of folic acid. Finally, the PPMAMCNTPE was effectively implemented for the voltammetric detection of AN in both injection and blood serum samples.