Study on intervention effect of artificial block of mother-to-fetus transmission of AIDS

Objective:To analyze the intervention effect of artificial block of mother-to-fetus transmission of AIDS,provide a scientific basis for further improving prevention and treatment of AIDS.Methods:The situation and effect of artificial block of mother-to-fetus transmission of AIDS from 2009 to 2013 were analyzed retrospectively by descriptive method.Results:From 2009 to 2013,the detection rate of HIV antibody was 63.76%( 20 798 /32 617),13 HIV-infected pregnant women were found,the detection rate of HIV was0.06%( 13 /20 798),2 women were found in the non-pregnant state;preventive antiviral block drug therapy during pregnancy or before delivery was performed among the HIV-infected mothers of 8 infants,the rate was 53.33%( 8 /15),the rate of neonatal preventive antiviral block drug therapy was 40.00%( 6 /15),artificial feeding of neonates was 66.67%( 10 /15);the effective rate of preventive antiviral block drug therapy in 8 mothers was 100.00%( 8 /8);among 7 infants whose mothers not receiving preventive antiviral block drug therapy,one infant died at 12 months after birth,HIV antibody of 4 infants was negative,while HIV antibody of 2 infants was positive;among the infants whose mothers not receiving preventive antiviral block drug therapy,the rate of mother-to-fetus transmission of HIV was 33.33%( 2/6),there was no statistically significant significance in the incidence rate of infantile HIV infection between infants whose mothers receiving preventive antiviral block drug therapy and infants whose mothers not receiving preventive antiviral block drug therapy because of low sample size( χ2= 0.98,P = 0.16).Conclusion:The risk of mother-to-fetus transmission of AIDS still exists,detection during pregnancy and preventive antiviral block drug therapy are key measures to block mother-to-fetus transmission of AIDS.