A preliminary analysis investigating immune activation in schizophrenia

This paper is an interrum analysis of a longitudinal project designed to ascertain whether immune activation is a trait marker for a small subset of patients with the syndrome we call schizophrenia. We present data from over 70 schizophrenic patients and 50 matched normal volunteers. The patients were evaluated on 2 occasions at least 30 days apart. The preliminary analyses suggest that some patients with schizophrenia may have an immune modulated component to their disorder and this seems to be a relatively stable trait marker of the syndrome for these patients.