Effects of Electrode Sizes and Positions on the Induced Current Field in Electrical Eyeballs Stimulations

At present, a large number of confirmatory studies have shown that electrical stimulation has been an important method for the treatment of ophthalmic diseases, but how to optimize the stimulation is still a problem to be solved. In this paper, the effects of electrode size and electrode position on the current and maximum current in different tissues in the head were studied by model simulation method with the SimNIBS software. The results showed that 1) both smaller size of stimulating electrode and the method of monocular bipolar transpalpebral electrical stimulation can effectively reduce the impact on gray matter and other tissues in brain; 2) choosing appropriate medium electrode size will reduce the current intensity in skin; 3) the method of monocular transorbital electrical stimulation can effectively enhance the induced current field in a larger range in the stimulated eyeball. The results of the study provided information potentially useful for formulating more effective plans for treating ophthalmic diseases with electrical stimulation methods.