Conclusions: The consumption of antihypertensive drugs in Extremadura increased remarkably in the last 23 years. In the last years the use of angiotensin II antagonist drugs is having a significant economic impact. Trends in Antihypertensive Drug Use in Spanish Primary Health Care (1990-

2015 
Objective: This study aimed to describe the use of antihypertensive in Extremadura (Spain) from 1990 to 2012
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